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What Causes Kidney Failure in Cats & Dogs | Billings Animal Family Hospital

What Causes Kidney Failure in Cats & Dogs | Billings Animal Family Hospital

July 31, 20255 min read

What Causes Kidney Failure in Cats (and How It Differs in Dogs)

Kidney failure is one of the more serious health conditions affecting our beloved pets. Understanding what causes kidney failure in cats, along with its manifestations in dogs, is crucial for early intervention, long-term management, and ensuring your furry friend receives the best quality of life.

In this guide, we break down the causes, stages, symptoms, and treatment of kidney disease in pets, providing a gentle and straightforward approach to help you feel informed and confident.


What causes kidney failure in cats?

If you've ever asked yourself, "what causes kidney failure in cats?" — you're not alone. Kidney failure can be either sudden (acute kidney failure) or develop gradually over time (chronic kidney disease, or CKD).

Common causes of kidney disease in cats

  • Aging: Especially in older cats, kidney tissue gradually breaks down.

  • Toxins: Ingesting antifreeze, lilies, or human medications.

  • Infections: Bacterial or viral infections that damage kidney tissue.

  • Genetics: Some breeds are prone to polycystic kidney disease.

  • Other Conditions: Dental disease, high blood pressure, and heart disease can lead to kidney damage.

Often, it’s not just one factor. Many cats experience kidney decline due to a combination of age, environmental factors, and underlying health conditions.

grey colored cat laying on top of bed

Understanding kidney function in pets

The kidneys are multitasking organs. They filter waste from the blood, balance fluids and electrolytes, regulate blood pressure, produce red blood cells, and activate vitamin D. At Billings Animal Family Hospital, we offer comprehensive veterinary services to assess and support kidney function at every stage of your pet’s life.

What happens when the kidneys fail?

When kidney function declines, waste accumulates in the bloodstream. This leads to a condition called uremia, which can cause vomiting, mouth ulcers, bad breath, and changes in behavior. Pets may also experience dehydration and lethargy.

Maintaining healthy kidney function is essential, not just for cats but also for dogs. The sooner a problem is detected, the more we can do to support recovery.

orange cat and white puppy on top of table with vet

Acute kidney failure in dogs and cats

Acute kidney failure happens quickly, often in response to toxin ingestion, dehydration, or infection. It can also occur after certain medications or surgery involving anesthesia.

Clinical signs of acute kidney injury

  • Vomiting or diarrhea.

  • Sudden lethargy.

  • Decreased appetite.

  • Little or no urine output.

  • Swollen abdomen or back pain.

This condition requires emergency veterinary treatment, as well as blood and urine testing, to confirm the diagnosis. In some cases, hospitalization and IV fluid therapy are necessary.

cat and dog laying in bed

Chronic kidney disease in cats and dogs

Chronic kidney disease is more common in older cats, typically developing over several months or years. It often goes unnoticed until later stages.

Signs of chronic kidney disease

  • Increased thirst and urination

  • Weight loss

  • Poor coat condition

  • Bad breath (uremic odor)

  • Muscle wasting

What makes chronic kidney disease different?

Unlike acute kidney problems, chronic disease is not reversible. However, symptoms can be managed, and progression can be slowed with proper care.

Cats with chronic kidney disease may be diagnosed during routine blood work or after signs of the disease appear. While there is no cure, early management can significantly improve your pet's quality of life.

Curious about more information? You can explore Cornell University’s CKD guide for additional insight.

Kidney failure in cats stages

Kidney failure in cats stages is categorized from mild to severe:

  • Stage 1: No symptoms; diagnosis based on blood and urine abnormalities

  • Stage 2: Mild weight loss, increased thirst

  • Stage 3: More apparent symptoms; elevated waste levels in blood

  • Stage 4: Severe symptoms, decreased quality of life

Understanding the stages of kidney failure helps vets determine treatment plans and prognosis.

Kidney failure in dogs stages

Similar to cats, kidney failure in dogs also follows a four-stage process. However, symptoms in dogs may be more variable.

  • Stage 1: No visible symptoms, but early kidney strain begins.

  • Stage 2: Mild vomiting, appetite loss, and pale gums appear.

  • Stage 3: Frequent vomiting, fatigue, and visible weight loss.

  • Stage 4: Severe symptoms, confusion, no appetite, high blood pressure.

Dogs in later stages may also develop high blood pressure or become disoriented. Monitoring and veterinary supervision are critical.

Understanding these stages can help you and your vet create a care plan to manage your pet’s chronic kidney disease and preserve kidney function.

gray cat (left) and golden retriever (right) sitting together

Treating and managing kidney disease in pets

While kidney failure isn’t curable, it is manageable. Treatment may include:

  • Special kidney-support diets with reduced protein and phosphorus

  • Fluids (subcutaneous or IV) to help with dehydration

  • Medications for blood pressure, nausea, and phosphorus control

  • Supplements like potassium or omega-3 fatty acids

  • Regular monitoring of red blood cell count and waste levels

A vet can guide you through the options to maximize your pet’s quality of life. For trusted care and support, visit Billings Animal Family Hospital to learn more about our commitment to pet health.

Preventing kidney problems in cats and dogs

While not all kidney issues are preventable, there are proactive steps you can take:

  • Keep pets well-hydrated

  • Feed a high-quality diet appropriate for their age

  • Schedule routine veterinary checkups

  • Monitor for changes in urine output or thirst

  • Avoid toxic plants and substances

  • Manage dental health to prevent bacteria from entering the bloodstream

An early diagnosis makes a significant difference, especially in cats that often hide symptoms.

cat and dog taken care by vet

Supporting pets with kidney disease

If you’re concerned about kidney failure in cats or dogs, early intervention is crucial. Understanding what causes kidney failure in cats can help you catch warning signs early and improve your pet's outcome.

Book a consultation with our team today to discuss your pet’s kidney health, testing options, or to talk through your concerns. Don't forget to download your Emergency Vet Contact Card to stay prepared for any unexpected situations. To learn more, please visit our About Page, where you can discover who we are and what we do in detail.

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